Edward Lawrie Tatum Born : December 14, 1909 Died : November 5, 1975 Browse All Authors Top 3 quotes by Edward Lawrie Tatum In microbiology the roles of mutation and selection in evolution are coming to be better understood through the use of bacterial cultures of mutant strains. Edward Lawrie Tatum mutation mutants culture As has repeatedly been stated, the underlying hypothesis, which in a number of cases has been supported by direct experimental evidence, is that each gene controls the production, function, and specificity of a particular enzyme. Edward Lawrie Tatum enzymes genes numbers That the primary effect of gene mutation may be as simple as the substitution of a single amino acid by another and may lead to profound secondary changes in protein structure and properties has recently been strongly indicated by the work of Ingram on hemoglobin. Edward Lawrie Tatum changes single simple work